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When it comes to stem cells, if you're left feeling like you don't know your adult from your embryonic, if you're confused by cloning or if you thought multipotency was an effect of Viagra, then our stem cell guide is for you. Ruth Williams gets down to the nitty-gritty [...] Scanning electron microscopic (SEM) image of a stem cell from human ...
Section: Content | Category: Features | Date: Friday, 01 August 2008 | Hits: 28783
Researchers take another step towards using "reprogrammed" stem cells (iPS) to treat a metabolic liver disorder.Young, S., 2011.Scientific American; October 12th [online] ...
Section: Content | Category: General epigenetics | Date: Tuesday, 12 June 2012 | Hits: 3902
So what's the advantage of using stem cells from the embryo that have been reprogrammed in this way? The main advantage is that you can derive a greater variety of cell types. Embryonic stem cells, as they are called, have the potential to be any body cell. Adult stem cells on the other hand have partly committed to different cell fates. So, for example, ...
Section: Content | Category: FAQ common | Date: Friday, 16 September 2011 | Hits: 64848
When you cut yourself, your body's defences are rapidly initiated at the wound site. Your own natural stem cells are recruited to make new skin. Different kinds of stem cells are present in each of your body organs to repair damaged tissue. These are adult stem cells. Scientists are excited about harnessing the power within these special cells to create ...
Section: Content | Category: FAQ common | Date: Friday, 16 September 2011 | Hits: 20134
Patients' own adult stem cells have been successfully used to treat a number of conditions, like Parkinson's disease and multiple sclerosis. If you take adult stem cells from other people, they might not be genetically compatible with the patient. Transplanted adult stem cells can be rejected. Another way to avoid rejection of stem cell transplants ...
Section: Content | Category: FAQ common | Date: Friday, 16 September 2011 | Hits: 6930
Two RISE 1 investigators have published a report mechanism that may lead to more efficient reprogramming of somatic cells The team of researchers around Maria-Elena Torres-Padilla (Institute of Genetics and Molecular and Cellular Biology, Strasbourg) and Juanma Vaquerizas (Max Planck Institute for Molecular Biomedicine, Münster) have managed to obtain ...
Section: Content | Category: News | Date: Wednesday, 19 August 2015 | Hits: 4462
Stefan Janusz reports on how genes are poised for transcription. Stem cell therapy holds the key to regenerative medicine: replace defunct or diseased cells in an organ by injecting new cells derived from a continually replenishing source. This kind of therapy often relies on the [...] Dicer was given its name by Emily Bernstein, a graduate ...
Section: Content | Category: In brief | Date: Thursday, 01 April 2010 | Hits: 12479
8. Primed
Stefan Janusz explains how new research is shaping our understanding of stem cell biology.Pluripotent embryonic stem (ES) cells can give rise to any of the multitude of cell types in the body, making them an exciting prospect for generating [...] July 2010 Stefan Janusz explains how new research is shaping our understanding of stem cell biology. Pluripotent ...
Section: Content | Category: In brief | Date: Tuesday, 01 June 2010 | Hits: 12582
Stefan Janusz reports on new ways of investigating embryo development. Stem cell therapy holds the key to regenerative medicine: replace defunct or diseased cells in an organ by injecting new cells derived from a continually replenishing source. This kind of therapy often relies on the [...] March 2010 Stefan Janusz reports on new ways of investigating ...
Section: Content | Category: In brief | Date: Monday, 01 March 2010 | Hits: 11797
By Dr Lindsey Goff Cancer is not just one disease with one cause. There are billions of cells in our body each home to a multitude of tightly-controlled biochemical activities. So there are numerous points where control can break down and cause cancer [...] A model of the histone deacetylase (HDAC) enzyme, the target of a new class of drugs By ...
Section: Content | Category: In brief | Date: Tuesday, 01 August 2006 | Hits: 16570
Pursuing your dream career can be a rather depressing experience. As you progress through school, you increasingly narrow the number of subjects you study, shutting doors to other paths even as you follow your long-held ambitions. Oddly enough, this is something you have in common with the cells in your [...] Developing cells, like humans, shut ...
Section: Content | Category: Features | Date: Monday, 03 September 2007 | Hits: 22353
... publication by researchers at the MRC Clinical Sciences Centre (Genome Function Group) has shown that genes supposedly hidden from transcriptional machinery can still be poised and ready to be expressed. The study focused on the urokinase-type plasminogen activator (uPA) in human HepG2 cells. Here it fits the 'standard model' of gene activation: sitting ...
Section: Content | Category: In brief | Date: Monday, 01 March 2010 | Hits: 11720
Response written by: Elphège Nora, PhD - postdoctoral researcher in Edith Heard's laboratory, Institut Curie Germ cells of human beings (and all other organism actually) are unfortunately unable to "copy" the skills and knowledge of their producer. Children/offspring, develop from the fusion of two gametes (germ cells), one from the mother and one ...
Section: Content | Category: FAQ common | Date: Friday, 09 November 2012 | Hits: 4029
“Ten years ago publication of the human genome sequence gave the world a blueprint for a human being. But just as a list of automobile parts does not tell us how a car engine works, the complete genome sequence—a list of the DNA "letters" in all the chromosomes of the human cell—did not reveal how the genome directs our cells' day-to-day activities ...
Section: Content | Category: General epigenetics | Date: Tuesday, 12 June 2012 | Hits: 5351
... act as master switches - controlling the maturation of cells in a developing embryo - might be relevant to cancer. Their hunch was based on the observation that cancer cells in many respects appear to be 'immature'. The team investigated a master gene (ato) involved in eye development in flies. The equivalent gene in humans (ATOH1) is a known tumour-suppressor. ...
Section: Content | Category: In brief | Date: Monday, 02 February 2009 | Hits: 12387